hmmm... I don't know about that. Compared to other shows, i think macross has been pretty subtle about its antagonists.
in sdfm, while britai and exedole were the first enemies, they eventually turned to the other side. Bodolza did not appear entirely evil the first time he appeared. while i admit Kaifun is the biggest ass in the macross universe, he appeared more as a romantic foil to hikaru and minmei in his first appearance. it wasn't until later that we saw how much of a jerk he really was.
in M+, sharon apple wasn't really the enemy until the last quarter. In Macross0, there were just 2 military sides fighting it out, anti-un wasn't necessarily evil.