The Nome family have genetic markers (perhaps everybody on that island...) which make them "special". The Nome family are the "pilots" of AFOS. The can interface with AFOS. And AFOS reacts to them.
Now, in AFOS's cockpit, there are a series of tubes that wrap around Sara. What those tubes are doing...I leave to your imagination, but Sara was very much "plugged in" to AFOS so it reacts to everything she sees, hears, feels, etc.